Anatomy/Muscular System

Muscular System
<Anatomy

Antagonistic Pairs
Muscles work in antagonistic pairs. This basically means that there are always at least two muscles working in opposite functions for any joint. One will, for example, extend the joint, while the other flexes it. A good example is the elbow joint. The Triceps brachii extends the joint when it contracts, and the Biceps brachii flexes the joint when it contracts.

Interactive animation to see this concept in action

Of course, there are never really only two muscles acting on a joint. In the scenario I just described, the Brachialis and Brachioradialis would be acting on the elbow in flexion with the Biceps, and the Anconæus would act with the Triceps, although it has a very minor function.

Three Types of Muscle
As the title of this section implies, there are three types of muscle: Skeletal, Cardiac, and Smooth.



Skeletal Muscle
Despite the fact that there are three types of muscle, skeletal muscle is the kind most stressed by the event. Science Olympiad requires you to know 50 skeletal muscles for the event. A comprehensive list can be found here. The skeletal muscle is the kind most commonly thought of when one hears the word "muscle". Examples include Vastus muscles, the Rectus abdominis, and the Biceps brachii.




 * A Tendon attaches muscle to bone. The Epimysium (plural epimysia) is a layer of dense connective tissue that surrounds the entire muscle. Its function is to protect muscles from friction that occurs between other muscles and bones.  In tendons, it is thicker and contains more collagen.
 * The muscle consists of many Fascicles (aka bundles) of muscle fibers. Each fasicle is wrapped in a connective tissue covering called the Perimysium.
 * The Endomysium consists mostly of reticular fibers. It is the sheath of connective tissue surrounding a fiber.

Anatomy of a Skeletal Muscle Fiber



 * The skeletal muscle fiber is a cell.
 * The Sarcolemma is the plasma membrane.
 * It has multiple inward extensions which form a set of T Tubules (the T stands for transverse).
 * The Sarcoplasm is the cytoplasm & the Sarcoplasmic Reticulum is the endoplasmic reticulum.
 * Myofibrils are the cylindrical organelles found inside a muscle fiber.
 * Myofilaments are the filaments of a myofibril.
 * Myofilaments are organized into repeating units called Sarcomeres.



When muscles contract, the I band and H zone decrease in length but the A band stays the same length.
 * Above is a picture of the structure of sarcomere.
 * There are two types of myofilaments. Myosin filaments are thick and Actin filaments are thin.
 * Z lines separate myofibrils into the compartments called sarcomeres.
 * I bands are where there are only thin filaments.
 * H zones are where there are only thick filaments.
 * A bands are all along the thick filaments. (some overlapping)

The NMJ and Muscle Contraction
The neuromuscular junction is the point where a motor neuron meets the muscle fiber. One motor neuron can form many NMJ's. The surface of the muscle fiber forms small ridged folds for the end of axon to rest in. Inside these folds are depressions with acetylcholine receptors. The folds are known as synaptic clefts.

Acetylcholine is necessary for life. It is the only neurotransmitter that is used in the motor division of the somatic nervous system, part of the peripheral nervous system that controls voluntary actions.

Muscular System Diseases
{|class="wikitable" !Disease !Cause !Symptoms !Prevention !Treatment !Muscular Dystrophies !Poliomyelitis !Myasthenia gravis !Tetanus !Fibromyalgia !Carpal Tunnel Syndrome Muscles have many important functions in the body. They:
 * +Muscular System Diseases
 * Genetic mutation
 * Muscle weakness, lack of coordination, frequent falling, ptosis (eyelid dropping)
 * No cure, medications, therapy
 * Genetic counseling, no known cure
 * Infection with the poliovirus
 * Fever, sore throat, vomiting, no appetite, stiffness
 * Polio immunization
 * Antibiotics, medications, physical therapy, pain killers
 * Nerve impulse to initiate or sustain movement does not reach the muscle cells sustain movement
 * Eyelid drooping, swallowing difficulty, double vision, trouble talking
 * Rest, avoid extreme temperatures and emotional stress
 * Medications, thymectomy, (removal of thymus gland)
 * Infection by the virus Clostridium tetani
 * Spasms in the jaw, chest, neck, back and abdominal muscles, which can lead to fractures, breathing, and muscle tears; drooling; fever; irritability; and problems with swallowing
 * The Tdap vaccine
 * Antibiotics; bed rest; medicine to reverse the poison (tetanus immune globulin); muscle relaxers; sedatives; surgery to clean the wound
 * Unknown
 * Long-term, body-wide pain and tender points in joints, muscles, tendons, and other soft tissues (deep-aching, radiating, gnawing, shooting or burning, and ranges from mild to severe)
 * Unknown
 * Medications, patient education, physical therapy, and counseling are usually recommended; in mild cases, symptoms may go away when stress is decreased or lifestyle changes are implemented
 * Common in people who perform repetitive motions of the hand and wrist, such as typing or painting
 * Avoiding repetitive motions. Ergonomic aids may help, as may tools designed to not hurt the wrist}
 * Enable movement
 * Aid in respiration (diaphragm)
 * Aid in digestion
 * Protect internal organs
 * Help move blood throughout the body