Lake Erie/Niagara Regional

The Lake Erie/Niagara region is located in Western New York. In 2018, 35 teams attended the C Division competition (with the top 5 qualifying for New York states).

C Division
{| class="wikitable sortable" style="text-align:center" ! Year ! Champion ! Runner-up ! Third Place ! Fourth Place ! Fifth Place ! Teams
 * 2019
 * Williamsville East High School
 * St. Joseph's Collegiate Institute
 * Williamsville North High School
 * ?
 * Clarence High School
 * 35
 * 35