Protein Modeling C

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CookiePie1
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Re: Protein Modeling C

Post by CookiePie1 » March 1st, 2020, 3:59 pm

WestMax wrote:
March 1st, 2020, 10:42 am
I'm attempting to learn as much as I can about CRISPR, but I feel lost because I either find sources that are way too in-depth and I cannot read them, or I find the most basic resources. Does anyone have any sources that are between the two, and I hate to say it but the fact that the rules only tell us to learn about CRISPR/Cas9 means I have no real idea what I should focus on and I'm stuck feeling like I'm either missing vital information or I'm going way to obscure. I have been to scioly.com and am currently going through their video series, but is that enough?
https://media.hhmi.org/biointeractive/click/CRISPR/ this website is pretty good for a basic understanding of the mechanism behind it. The videos on the CBM website are pretty good for a start as well. However, if you want to start going more in-depth about the topic you kinda have to start reading the research papers about it. I also reccomend going on the CBM website and finding last year's papers, which are also pretty good.
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Re: Protein Modeling C

Post by rish-leti » March 1st, 2020, 6:41 pm

Does anyone have any tips on what to study for the jmol portion once past the basics? I'm fairly solid on biochemistry and manipulating jmol, but I dont really know what to study next because it seems like every single test throws something a little bit different at us. Should I be studying different types of proteins, or delving deeply into CRISPR/CAS9? Thank you!
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Re: Protein Modeling C

Post by CookiePie1 » March 1st, 2020, 7:11 pm

rish-leti wrote:
March 1st, 2020, 6:41 pm
Does anyone have any tips on what to study for the jmol portion once past the basics? I'm fairly solid on biochemistry and manipulating jmol, but I dont really know what to study next because it seems like every single test throws something a little bit different at us. Should I be studying different types of proteins, or delving deeply into CRISPR/CAS9? Thank you!
At SOUP, the test writer kinda threw curveballs at us by asking us to identify random proteins. That's easy enough, given jmol, but then we were asked a bunch of questions about its function and random info about said proteins. So, maybe it is a good idea to study some stuff about different commonly studied proteins. The PDB MOTM is a good place to start for that. Also, delving deeply into crispr/cas9 is always a good idea given the topic for this year.

Maybe the soup test was a bit of an anomaly though.
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Re: Protein Modeling C

Post by Jashan12 » March 4th, 2020, 4:05 pm

What is a score to get you to place going to be like on like with everything overall. (Ex 70% on model, 99% on onsite, and 1% on test)?

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Re: Protein Modeling C

Post by CookiePie1 » March 4th, 2020, 4:36 pm

Jashan12 wrote:
March 4th, 2020, 4:05 pm
What is a score to get you to place going to be like on like with everything overall. (Ex 70% on model, 99% on onsite, and 1% on test)?
Depends on the competion, since every test is different and every tournament has different teams.
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Protein Modeling C

Post by NationalsAim » March 6th, 2020, 6:13 pm

Anyone have any tips for identifying good sidechains to include in the Pre-Build Model?

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Re: Protein Modeling C

Post by CookiePie1 » March 6th, 2020, 7:30 pm

NationalsAim wrote:
March 6th, 2020, 6:13 pm
Anyone have any tips for identifying good sidechains to include in the Pre-Build Model?
you should read the papers on the cbm website. A lot is detailed in there.
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Re: Protein Modeling C

Post by MoMoney$$$;)0) » March 23rd, 2020, 10:45 am

Come on people we need to add to the best of 2020

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Re: Protein Modeling C

Post by tjmontgomery » July 29th, 2020, 4:59 pm

Hi. Does anyone have any information on if the pre-built for the 2021 competition is the same as last year or is it different? I know Protein Modeling is supposed to have a rule change but I am not sure what that will entail. Thanks

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Re: Protein Modeling C

Post by CookiePie1 » July 30th, 2020, 7:30 am

tjmontgomery wrote:
July 29th, 2020, 4:59 pm
Hi. Does anyone have any information on if the pre-built for the 2021 competition is the same as last year or is it different? I know Protein Modeling is supposed to have a rule change but I am not sure what that will entail. Thanks
I think they meant that they would change the topic and therefore change the prebuild. This is just speculative though. Nobody really knows what's going on right now lol.
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