Protein Modeling C

kwijiborjt
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Re: Protein Modeling C

Post by kwijiborjt » June 17th, 2011, 7:49 pm

Yeah, especially given that it's impossible to take all subjectivity out of the model judging, I think it's best to regard your placement in this event as placing you in a range rather than a position. I've had events where five teams were separated by less than half a point (that easily could have been granted or taken away on subjective calls).
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Re: Protein Modeling C

Post by Phenylethylamine » June 17th, 2011, 8:03 pm

FullMetalMaple wrote: Definitely. I saw at least two instances where teams were only .01 points apart. That's incredible. Good job to everyone!
It looks like that was how they designated a tiebreaker- i.e., if two teams had the same score, the one that did better on the tiebreakers received an extra .01 point.
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Re: Protein Modeling C

Post by kwijiborjt » June 17th, 2011, 8:33 pm

Uhhh... is question #10 wrong on the 2011 national exam answer key?
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Re: Protein Modeling C

Post by FullMetalMaple » June 17th, 2011, 9:14 pm

Phenylethylamine wrote:
FullMetalMaple wrote: Definitely. I saw at least two instances where teams were only .01 points apart. That's incredible. Good job to everyone!
It looks like that was how they designated a tiebreaker- i.e., if two teams had the same score, the one that did better on the tiebreakers received an extra .01 point.
That's what I thought, too.
kwijiborjt wrote:Uhhh... is question #10 wrong on the 2011 national exam answer key?
...Yes, I think it is. It's induced pluripotent stem cells that can't produce trophoblast and placenta, whereas totipotent can. Shouldn't it be A instead of D? The same question was on the regional test, with the answer choices in the same order, and the correct answer is A there.

Otherwise, the test looked great. Again, I wish I could have been at nationals.

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Re: Protein Modeling C

Post by Phenylethylamine » June 18th, 2011, 6:43 am

After seeing my prebuild score (35.75/40) on that spreadsheet, I assumed that I must not have gotten credit for some creative additions... but having read the rubric, I had literally every one of the creative additions specifically mentioned. I really have no idea where I lost that many points, especially since the checklist for the secondary and tertiary structure sounds almost exactly like what I myself did at home before competition. I can only guess that maybe I lost points if they didn't feel my extra creative additions (not mentioned in the rubric) were sufficiently related to the function of the protein? I could see a half- or quarter- point here or there, but I can't figure out how I lost 4.25 points.

Oh well. I'll be posting photos of my model and card in the image gallery as soon as I get around to actually taking said photos.
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Re: Protein Modeling C

Post by kwijiborjt » June 21st, 2011, 9:26 am

Is it possible that you made mistakes on your creative additions? I didn't give credit for some additions if their explanations suggested that competitors knew the right words but not what the concept actually meant. Often there are errors in modeling too (docking the protein in DNA that is way off scale, docking it transverse rather than in a groove, failing to display a major and minor groove, placing the zinc ions in the wrong area, showing residues pointing the wrong way or positioned in the wrong place on the backbone, etc.).
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Re: Protein Modeling C

Post by Phenylethylamine » June 21st, 2011, 12:56 pm

kwijiborjt wrote:Is it possible that you made mistakes on your creative additions? I didn't give credit for some additions if their explanations suggested that competitors knew the right words but not what the concept actually meant. Often there are errors in modeling too (docking the protein in DNA that is way off scale, docking it transverse rather than in a groove, failing to display a major and minor groove, placing the zinc ions in the wrong area, showing residues pointing the wrong way or positioned in the wrong place on the backbone, etc.).
Well, you've seen my model. The protein was clearly correctly placed relative to the DNA, and I adjusted it post-States to be more to scale (not that it was very far off to begin with). I made sure that I understood the function of all the sidechains I modeled, and was very careful to position them according to the Jmol structure.

While I suppose it's possible that I made mistakes in some of my creative additions, I can't find any such mistakes.
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Re: Protein Modeling C

Post by kwijiborjt » June 22nd, 2011, 4:45 am

Hmm... i don't know then. There are so many places for slight deductions. But if you model with that level of specificity you'll do very well on *my* exam next year :)
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Re: Protein Modeling C

Post by butter side up » June 24th, 2011, 6:59 am

kwijiborjt wrote:Hmm... i don't know then. There are so many places for slight deductions. But if you model with that level of specificity you'll do very well on *my* exam next year :)
OK, I'll take the bait. Any hints on what would be good to study over the summer and into next year? *crosses fingers*
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Re: Protein Modeling C

Post by Infinity Flat » June 24th, 2011, 10:54 am

butter side up wrote:
kwijiborjt wrote:Hmm... i don't know then. There are so many places for slight deductions. But if you model with that level of specificity you'll do very well on *my* exam next year :)
OK, I'll take the bait. Any hints on what would be good to study over the summer and into next year? *crosses fingers*
Probably what they already have up on the website: Apoptosis and the specific proteins. There is also a short documentary about the disease that one of the proteins (XIAP) can cause, so you could watch that as well.
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